Independence Plaza is ideally situated on Seventeenth Street, downtown Denver's "Wall Street of the West," as well as the popular 16th Street Mall. This location affords the convenience of a variety of retail services. The building currently houses:
| AT&T | Suite A125 |
| AlphaGraphics Print Shop | Suite B199 |
| Stan's Downtown Barbers II | Suite B170 |
| Shoe Shine Services | Lobby |
| Juice Kitchen | Suite B195 |
| Rock Bottom Brewery | Suite A100 |
| Tokyo Joe’s | Suite A140 |
| Wells Fargo Bank | Suite 100 |
| Woody Creek Bakery & Cafe | Suite A130 |
U.S. Mail drop boxes located on the first floor.